In order to investigate the effects of planting date and first irrigation date on growth and yield of saffron an experiment under Nasrabad climatic condition of Torbat-e Jam city in 2017 - 2018 was carried out as a split plot based on randomized complete blocks design with three replications. Experimental treatments were six planting dates (22 May, 5 June, 22 June, 6 July, 23 July and 6 August) as main plots and three irrigation times: irrigation after each planting, irrigation on 21 August and irrigation based on custom region on 7 October (control) as sub plots. In this study, number of flowers, flowers fresh weight, stigma fresh and dry weight, crocin, picrocrocin and safranal were measured. Results showed yield and components of yield decreased by delaying in planting date and irrigation after each planting. In the first and second years of the experiment, respectively, the highest number of flowers per m2 (16.41 and 49.35), the highest fresh flower yield (47.60 and 127.73 kg/ha), the highest fresh stigma yield (4.09 and 12.95 kg/ha), and the highest dry stigma yield (714 and 2841 g/ha) were obtained on May 22 planting date with combination with irrigation on August 21. All treatments had no significant effect on crocin content. The maximum content of picrocrocin (111.33 mg/g) and safranal (53.77 mg/g) recorded on 21 August irrigation treatment. Picrocrocin content decreased by delaying in planting date and the highest of picrocrocin was observed on 22 May and 5 June. Based on the results, it was recommended that saffron planting from 22 May until 6 July, no irrigation after planting and irrigation on 21 August are good method for saffron production.